Neuraminidase Inhibitors

Inhibiting neuraminidase inhibits influenza


Pegylated interferon
Video: Neuraminidase Inhibitor Mechanism of Action


  • When viral replication is not inhibited, the influenza virus spreads quickly both within the host and to those in contact with the infected patient.


The illustrations below show the difference between inhibited and non-inhibited influenza virus.

Viral neuraminidase: key to releasing influenza virus from infected cells13

Influenza Infection





Neuraminidase inhibition


Therapeutic options and sites of action

Options Site of activity on virus
Neuraminidase inhibitors Neuraminidase enzyme
M2 inhibitors M2 protein ion channel
OTC medications none

Neuraminidase inhibitor mode of action helps prevent viral proliferation, which helps stop the spread of influenza.

Learn more about a prescription neuraminidase inhibitor for flu treatment and prophylaxis.

Next topic: Flu Surveillance

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